Dreams involving guilt and responsibility, especially in relation to death, can be quite profound and often reflect our subconscious thoughts and feelings. In your dream, feeling responsible for the death of a lady and attempting to cover it up suggests that you may be grappling with feelings of guilt or regret in your waking life. This could relate to a specific situation where you feel you may have let someone down or made a mistake that negatively affected others.

The presence of the deceased's sister in your dream indicates a connection to familial ties and the impact of your actions on others. Your fear of being pursued by spirits may symbolize a fear of facing the consequences of your actions or unresolved issues that haunt you. This could also represent anxiety about how others perceive you or the fear of facing the truth.

Consider reflecting on any current situations or relationships in your life where you might feel a sense of guilt or responsibility. This dream could be prompting you to confront these feelings and seek resolution. It might be helpful to communicate openly with those involved or to find ways to forgive yourself for perceived shortcomings.

Overall, this dream serves as a reminder to acknowledge your feelings and to take steps towards healing and resolution in your waking life.